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小鼠骨钙素ELISA试剂盒
名称 小鼠骨钙素ELISA试剂盒
型号
更新时间 2023-09-24
特点 Mouse Osteocalcin ELISA Kit INTENDED USE:This kit is intended for research use only in the determination of mouse osteocalcin levels in serum, plasma or cell culture media.}
  • 详细内容

一.产口名称:
通用名称:小鼠骨钙素ELISA检测试剂盒
英文名称: Mouse Osteocalcin ELISA Kit

二.Mouse Osteocalcin ELISA Kit INTRODUCTION
Mouse osteocalcin, a 46 amino acid peptide, is the major noncollagen protein found in mouse bone. It contains three gamma-carboxyglutamic acid (GLA)residues at positions 13, 17, and 20 and is, therefore, also known as bone gla-protein or BGP. The exact biological function of osteocalcin is not known but the three gamma-carboxyglutamic acid residues confer on it a very strong ability to bind to hydroxyapatite and calcium.Vitamin K is essential for the biosynthesis of osteocalcin which is stimulated by 1,25dihydroxyvitamin D. Osteocalcin is synthesized by osteoblasts during the process of bone formation and mostly incorporated into bone matrix with some escaping into the blood. Since the half-life in blood is relatively short (about 5 minutes)the osteocalcin level in blood reflects new protein synthesis and therefore its measurement provides a valuable tool for assessing skeletal metabolism. Mouse Osteocalcin ELISA Kit  As a product unique to the osteoblast, it also represents the activity of the cell responsible for the formation of bone.

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