名称 | Recombinant Human M-CSF |
型号 | |
更新时间 | 2023-09-24 |
特点 | M-CSF是一个有效的造血因子由多种细胞包括淋巴细胞、单核细胞、成纤维细胞、内皮细胞、成肌细胞和成骨细胞。这是一个细胞增殖的关键调节器,分化,和生存的血液单核细胞、组织巨噬细胞。M-CSF临床上用于治疗感染,恶性肿瘤和动脉粥样硬化。它促进骨髓移植后造血恢复。} |
产品展示 / PRODUCTS
- 详细内容
一.产品名称:Recombinant Human M-CSF/Peprotech M-CSF
二.Catalog Number:AF-300-25
三.Synonyms:Macrophage Colony Stimulating Factor, CSF-1, MGI-IM
四.Description:
M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits. Manufactured using all non-animal reagents.
五.AA Sequence:
MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
九.Cross Reactivity:Monkey, Mouse, Rat, Human
产品搜索
联系我们
电话/传真:13366128764
手机:15311648455
地址:北京市海淀区厢黄旗2号楼1层4-179室