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Recombinant Murine SCF
名称 Recombinant Murine SCF
型号
更新时间 2023-09-24
特点 SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic}
  • 详细内容

一.产品名称:Recombinant Murine SCF

二.Catalog Number:AF-250-03

三.Synonyms:Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

四.Description:

SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Manufactured using all non-animal reagents.

五.AA Sequence:

MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

六.Source:E.coli

七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 10.0 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

九.Cross Reactivity:Human, Monkey, Rat, Mouse

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