名称 | Recombinant Human VEGF165 |
型号 | |
更新时间 | 2023-09-24 |
特点 | VEGF是一个强有力的增长和血管生成细胞因子。它刺激内皮细胞的增殖和生存,促进血管生成和血管通透性。用血管化组织中表达,VEGF在正常和病理血管生成中起着重要的作用。重组人类VEGF是38.2 kDa disulfide-linked homodimeric两个165个氨基酸组成的蛋白质多肽链。使用所有无动物生产试剂。} |
产品展示 / PRODUCTS
- 详细内容
一.产品名称:Recombinant Human VEGF165
二.Catalog Number:AF-100-20
三.Synonyms:
Vascular Endothelial Growth Factor, VPF, Folliculoslate cell-derived growth factor, Glioma-derived endothelial cell mitogen
四.Description:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Manufactured using all non-animal reagents.
五.AA Sequence:
APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.
九.Cross Reactivity:
Cow, Green Algae, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout, Human
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